Melanie McGuire: Astonishing Suitcase Murder Stuns New Jersey

Last week’s blog told the story of Richard Dabate, whose murder of his wife unraveled because of data extracted from her Fitbit. This week, we review the “suitcase murder” committed by Melanie McGuire. On April 28, she drugged her husband, Bill McGuire, and shot him to death. She then dismembered his body, placed the parts in three suitcases, and dumped them in Chesapeake Bay.

Melanie McGuire

Melanie McGuire was born and raised in New Jersey. After graduating from Rutgers University in 1994, she attended nursing school, graduating second in her class in 1997. In 1999, she married William T. “Bill” McGuire, a United States Navy veteran who worked as a software engineer.

Bill and Melanie McGuire (ABC News / 20/20)
Bill and Melanie McGuire (ABC News / 20/20)

In April 2004, the McGuires and their two sons lived in an apartment in Woodbridge Township, New Jersey. They planned to move into a house in Warren County, New Jersey. The couple closed on the house on April 28, but they never moved in.

Melanie McGuire Commits Murder

A week later, on May 5, two fishermen and two children found a suitcase containing human legs. The luggage had drifted ashore on the Chesapeake Bay Tunnel’s fourth artificial island. Virginia authorities launched a murder investigation.

William T. "Bill" McGuire (ABC News)
William T. “Bill” McGuire (ABC News)

On May 11, a graduate student cleaning up beach litter in the Fisherman Island National Wildlife Refuge found a second suitcase. This one contained a human head and torso. The head had one bullet wound, while the torso had two gunshot wounds in the chest. On May 16, a third suitcase containing the deceased’s arms washed ashore.

The second suitcase washed ashore on the beach at the Fisherman Island National Wildlife Refuge (Court TV)
The second suitcase washed ashore on the beach at the Fisherman Island National Wildlife Refuge (CourtTV)

Investigators released a facial reconstruction of the murder victim to the public. One of Bill McGuire’s friends recognized it, promoting Melanie McGuire to the unenviable position of prime suspect.

It now appeared that the murder occurred in New Jersey. Virginia authorities turned the investigation over to the New Jersey State Police.

Evidence Mounts Against Melanie McGuire

Detectives soon learned that Melanie bought a .38 caliber handgun in Easton, Pennsylvania, on April 26, two days before the murder. Her receipt also showed an unspecified item priced at $9.95. Only two things in the store had a $9.95 selling price. One of those was a box of .38 caliber wadcutter bullets, the type of bullet that killed Bill McGuire.

Receipt for a .38 caliber handgun purchased two days before the murder
Receipt for a .38 caliber handgun purchased two days before the murder

Investigators conducted forensic tests on the plastic bags used to dispose of Bill’s body. They compared those with the bags used to hold Bill’s clothes, which Melanie had given away. Tests proved that both sets of bags came from the same production line within hours of each other. This implied that Melanie had been the one to bag up Bill’s body and his clothes.

Dr. Bradley Miller testifies in court (CourtTV)
Dr. Bradley Miller testifies in court (CourtTV)

Police also learned that Melanie had been conducting a long-term affair with Dr. Bradley Miller, one of her coworkers at the fertility clinic where she worked.

Melanie’s Trial and Conviction

On June 2, 2005, police arrested Melanie right after she dropped off her children at school. Almost three years later, her trial began on March 5, 2007.

Melanie McGuire mugshot (Wikipedia)
Melanie McGuire mugshot (Wikipedia)

Prosecutors contended Melanie killed Bill to start a new life with her lover, Bradley Miller. Melanie insisted she was innocent. She also claimed that Bill was a compulsive gambler who became increasingly moody and unpredictable. This was an odd gambit since it was irrelevant if Melanie were innocent.

Melanie McGuire in court (The Star Ledger)
Melanie McGuire in court (The Star Ledger)

On April 23, 2007, Melanie McGuire’s jury found her guilty. They convicted her of first-degree murder, perjury, desecration of human remains, and possession of a weapon for an unlawful purpose. On July 19, 2007, she received a life sentence.


Despite appeals and questionable claims that her counsel was ineffective, Melanie McGuire remains in prison. She will be eligible for parole in 2073 when she is 100 years old. Her current home (2023) is the Edna Mahan Correctional Facility for Women in Clinton, New Jersey.

A recent prison mugshot of Melanie McGuire. She is incarcerated under her maiden name, Melanie Slate. (New Jersey Department of Corrections)
A recent prison mugshot of Melanie McGuire. She is incarcerated under her maiden name, Melanie Slate. (New Jersey Department of Corrections)

You can read more about Melanie McGuire and the “suitcase murder” in John Glatt’s 2008 book, To Have and To Kill.

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2 Replies to “Melanie McGuire: Astonishing Suitcase Murder Stuns New Jersey”

  1. Absolutely no DNA anywhere yet she was convicted by the media from day one–very sad case. I am a court reporter involved in several major NJ sensational trials.

  2. I’ve watched the Melanie McGuire interview at least 3 times over a period of a year or more, and still conclude that she planned and executed the murder of her husband, Bill McGuire.

    To begin with, Ms. McGuire’s sense of self-importance and superiority made it difficult for me to take her seriously at first, but once I was able to move past that issue, I began to look at the totality of the evidence. Most was circumstantial, but there’s such a thing as good circumstantial evidence and bad circumstantial evidence, and in this case, I believe the mountain of good circumstantial evidence could not all be explained away. There were just too many coincidences involved.

    Take for instance, the computer searches on how to poison someone and how to purchase a gun illegally or without a permit, the out-of-state purchase of a .38 caliber firearm and wadcutter ammunition– the same type of weapon and amo that killed her husband, the forged prescription pad that belonged to the doctor she worked with at the clinic, the green Kenneth Cole pieces of luggage that matched what she had at home, the same medical towels that her clinic uses, the trash bag his body parts were found in which matched the ones she packed his clothes in by manfacturer and production line, the Ez-pass that registered her vehicle that she tried to have removed, failing to disclose her affair at work until police confronted her about it.

    I believe Ms. McGuire wanted to end her marriage to Bill McGuire. She admitted being madly in love with her boss, the doctor, but she also wanted to purchase that dream home more than anything, though she couldn’t qualify for the loan without her husband. So, the night they closed escrow, she spiked his drink with the heavy drug she filled at the pharmacy using the forged prescription pad, dropped her children off at school the next day, laid out tarps in the bathtub, put a pillow over his head and chest before shooting him, drained all his blood into a container or bag by using a hypodermic needle and tubing obtained from her workplace, dismembered him with medical precision (she was a registered nurse), stuffed his body parts in 3 pieces of luggage, hauled them out to her vehicle that was already lined with a tarp, drove out to the Chesapeake Bay and disposed of him, never thinking the luggage would surface..

    According to the police, none of Bill McGuire’s friends or associates said he was a heavy gambler—only that he gambled occasionally. Investigators also stated they found no evidence he owed gambling debts to anyone.

    It’s not much of a stretch to believe she more than likely assumed the doctor she was having an affair with would eventually leave his wife and family, marry her, and they would live, at least for awhile, in the new dream home she’d just purchased.

    Melanie McGuire’s over-confidence that she was the smartest person in the room was what led to her downfall, and I believe she’s right where she needs to be—behind bars for killing an innocent man.

    I’ve always been a strong advocate for the presumption of innocence until proven guilty beyond a reasonable doubt, but in this case, the prosecution put together an excellent extrapolation of events and circumstances that I believe proved their case hands down.

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